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The utility of intercostal respiratory muscle ultrasound scanning to predict which patients can be taken off the ventilator and its ability to identify patients who succeed in remaining off ventilatory support.

ROLE OF PARASTERNAL INTERCOSTAL MUSCLE ULTRASOUND DURING WEANING FROM MECHANICAL VENTILATION AND PREDICTION OF EXTUBATION SUCCESS IN ICU ââ?¬â?? A PROSPECTIVE OBSERVATIONAL STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/07/026427
Enrollment
60
Registered
2020-07-08
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J960- Acute respiratory failure

Interventions

None listed

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age > 18 years 2. Duration of mechanical ventilation >48 hrs. 3. Eligible for a spontaneous breathing trial as decided by the intensivist, according to established guidelines.

Exclusion criteria

Exclusion criteria: 1. Pregnancy 2. Patients with spinal cord injury at or above T12 3. Presence of significant arrhythmias 4. Patients with diaphragmatic paralysis/injury 5. Planned extubation into non-invasive ventilation / High flow nasal cannula (HFNC) 6. Surgical dressing significantly interfering with ultrasonography.

Design outcomes

Primary

MeasureTime frame
To determine whether the parasternal intercostal muscle thickening fraction measured by ultrasonography is useful in predicting weaning outcomes.Timepoint: Parameters noted before and after a 30 minute spontaneous breathing trial. Outcome assessed after forty eight hours of planned extubation—

Secondary

MeasureTime frame
4. To study other variables during ICU stay associated with weaning outcomes.Timepoint: Parameters noted before a spontaneous breathing trial and after the spontaneous breathing trial, if successful. Outcome assessed after forty eight hours of planned extubation;To assess various combinations of parameters and their ability to predict weaning outcomes.Timepoint: Parameters noted before a spontaneous breathing trial and after the spontaneous breathing trial, if successful. Outcome assessed after forty eight hours of planned extubation.;To determine the possibility of a composite index made up of echocardiographic parameters of systolic/diastolic cardiac function, ultrasound parameters of respiratory muscle function and LUS score, before and after SBT for predicting weaning outcomesTimepoint: Parameters noted before a spontaneous breathing trial and after the spontaneous breathing trial, if successful. Outcome assessed after forty eight hours of planned extubation;To observe the role of abdominal muscles in weaning process.Timepoint: Parameters noted before a spontaneous breathing trial and after the spontaneous breathing trial, if successful. Outcome assessed after forty eight hours of planned extubation—

Countries

India

Contacts

Public ContactDr Puneet Khanna

All India Institute of Medical Sciences

k.punit@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026