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Use of vitmin C for prevention of pain after surgery

Effect of intravenous infusion of Ascorbic acid on hyperbaric bupivacaine spinal block characteristics in infraumbilical surgeries: a prospective, randomized, double blind, placebo controlled study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/07/026425
Enrollment
64
Registered
2020-07-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N23- Unspecified renal colic

Interventions

Intervention1: SPINAL ANAESTHESIA: ASCORBIC ACID 50mg/kg in 50ml NORMAL SALINE INTRAVENOUS INFUSION GIVEN OVER 30MIN BEFORE GIVING SPINAL ANAESTHESIA Control Intervention1: SPINAL ANAESTHESIA: 50 ML N

Sponsors

SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: AGE 18-65 YEARS EITHER GENDER AMERICAN SOCIETY OF ANAESTHESIOLOGISTS PHYSICAL STATUS(ASAPS) 1,2,3 INFRAUMBILICAL SURGERIES UNDER SPINAL ANAESTHESIA

Exclusion criteria

Exclusion criteria: ALLERGIC TO STUDY DRUGS COAGULATION ABNORMALITIES PSYCHIATRIC AND NEUROLOGICAL DISORDERS UNWILLING TO PARTICIPATE IN THE STUDY UNABLE TO GIVE INFORMED CONSENT PREGNANT AND LACTATING WOMEN WHO CANNOT UNDERSTAND OR INTERPRET NUMERICAL RATING SCALE(NRS) FOR PAIN

Design outcomes

Primary

MeasureTime frame
1. Duration of analgesia 2. Total analgesic consumption in 24hoursTimepoint: 24 HOURS

Secondary

MeasureTime frame
1. Onset of sensory block 2. Onset of motor block 3. Duration of motor block 4. Time taken for two segment regression 5. Highest level of sensory block 6. Adverse hemodynamic effects during the study period 7. Magnitude of pain assessed by Numerical Rating Scale (NRS)Timepoint: 0.5,1,2,4,6,24 HOURS

Countries

India

Contacts

Public ContactRAYAVARAPU ANILA

SRI VENKATESWARA INSTITUTE OF MEDICAL SCIENCES

aloksvims@gmail.com9493547653

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026