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Study to compare the need for mechanical ventilation in babies born less than 32 weeks or birth weight less than 1.5 kg who are given surfactant( a drug given for lung maturation) by two different methods , one via a thin catheter (LISA) other by using endotracheal tube( INSURE)

Comparison of LISA with INSURE in reducing need for mechanical ventilation in very low birth weight preterms of � 32 weeks - A prospective observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/07/026405
Enrollment
186
Registered
2020-07-07
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J988- Other specified respiratory disorders

Interventions

None listed

Sponsors

SAT hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All preterms less than or equal to 32 weeks gestational age and/or less than or equal to 1.5 kg who are having Respiratory distress syndrome and needs surfactant

Exclusion criteria

Exclusion criteria: All outborn babies Major congenital anomalies

Design outcomes

Primary

MeasureTime frame
To compare Less Invasive Surfactant Administration (LISA) with INSURE technique of surfactant administration in terms of need for mechanical ventilation in the first 72 hours of life in preterm infants of less than or equal to 32 weeks AND / less than or equal to 1.5 kg .Timepoint: first 72 hours of life—

Secondary

MeasureTime frame
NilTimepoint: Nil—

Countries

India

Contacts

Public ContactDr Radhika S

Government Medical College, Trivandrum

radhikaajith@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026