Health Condition 1: I744- Embolism and thrombosis of arteries of extremities, unspecified Health Condition 2: null- Peripheral arterial occlusive disease
Conditions
Interventions
None listed
Sponsors
Christian Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: All patients presenting to the Vascular Surgery department in the outpatient clinic and or in patients diagnosed to have peripheral arterial occlusive disease will be included
Exclusion criteria
Exclusion criteria: Connective tissue disorders, Traumatic peripheral arterial disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the proportion of heme oxygenase-1 functional polymorphisms with genotype in case and control groupTimepoint: From the previous study [Schillinger et al, 2002], we assumed this proportion in controls to be 5%. Assuming an odds ratio of 5, a power of 80% and a 5% level of significance, the total sample size was 96 (32 cases and 64 controls). Schillinger M, Exner M, Mlekusch W, Domanovits H, Huber K, Mannhalter C, Et Al. HemeOxygenase-1 Gene Promoter Polymorphism Is Associated With Abdominal Aortic Aneurysm. Thromb Res. 2002;106(2):131â??136. | — |
Secondary
| Measure | Time frame |
|---|---|
| To study the polymorphisms in relation to the severity of the disease. (claudicants & critical limb ischaemia)Timepoint: 2 years | — |
Countries
India
Contacts
Public ContactAlbert Abhinay Kota
Department of Vascular Surgery Christian medical college and hospital Vellore, Tamil Nadu India
Outcome results
None listed