Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere Health Condition 2: J128- Other viral pneumonia
Conditions
Interventions
Intervention1: Prone positioning: Prone positioning for at least 30 min upto 16 hours per day till room air saturation is above 93% or till intubation
Control Intervention1: Supine position (as usual
Sponsors
Anant Mohan
Anjan Trikha
Karan Madan
Pawan Tiwari
Randeep Guleria
Saurabh Mittal
Sryma PB
Vijay Hadda
Eligibility
Inclusion criteria
Inclusion criteria: a) All adults > 18 years of age with acute hypoxemic respiratory failure with room air saturation b) COVID -19 positive by RT- PCR or COVID-19 suspected as the most probable clinco-radiological diagnosis of acute respiratory failure
Exclusion criteria
Exclusion criteria: 1) Age 70 yrs; 2) Severe ARDS P/F 3) PaCO2 >50 mm Hg; 4) Glasgow Coma Scale 5) Unable to spontaneously clear secretions from the airways 6) Requirement of emergency intubation for cardiopulmonary resuscitation, respiratory arrest, severe hemodynamic instability 7) Refusal to receive NPPV/ HFNC/ NRBM 8) Unable to cooperate with NPPV/ HFNC/ NRBM application 9) Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study the rate of invasive mechanical ventilation in patients treated with awake proning along with non-invasive methods of oxygen delivery in patients of COVID -19 positive acute hypoxemic respiratory failureTimepoint: till discharge or intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To study the improvement in oxygenation parameters (SO2, SO2/ FiO2, PaO2/ FiO2 ratio and ROX index) in patients undergoing prone positioning 2. Duration of hospital stay Timepoint: till discharge or intubation | — |
Countries
India
Contacts
Public ContactAnant Mohan
AIIMS
Outcome results
None listed