A study on the effect of the drug dexmedetomidine given before surgery on decreasing confusion and agitation in children after general anaesthesia using the gas sevoflurane.

Premedication with single dose of dexmedetomidine for reduction of emergence delirium in paediatric patients with sevoflurane based anaesthesia : a randomized double blind study.

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/07/026323

Enrollment

Registered

2020-07-02

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R418- Other symptoms and signs involvingcognitive functions and awareness

Interventions

Intervention1: Dexmedetomidine hydrochloride: Inj Dexmedetomidine hydrochloride, intravenous, at the dose of 0.5 micro grams per Kilogram of body weight, in 0.9% Sodium chloride, over 10 minutes, prio

Eligibility

Inclusion criteria

Inclusion criteria: Patients belonging to American Society of Anaesthesiologists Grades 1 and 2 and patients scheduled for elective surgeries requiring general anaesthesia

Exclusion criteria

Exclusion criteria: 1. Refusal of consent 2. Intellectual disability 3. Neurological diseases with agitation like symptoms 4. Allergy to dexmedetomidine

Design outcomes

Primary

Measure	Time frame
To compare the incidence of emergence delirium after premedication with single dose of intravenous dexmedetomidine, and placebo.Timepoint: Immediately after extubation, at 5 minutes, 10 minutes, 15 minutes, 30 minutes, 45 minutes, and 60 minutes from the time of extubation.	—

Secondary

Measure	Time frame
1.To observe the effects on pain, and nausea and vomiting in the immediate post operative period.Timepoint: At 5 minutes, 10 minutes, 15 minutes, 30 minutes, 45 minutes and 60 minutes from the time of extubation.;2.To record other relevant observations, if any.Timepoint: From 5 minutes prior to administration of the drug, till 60 minutes after extubation.	—

Countries

India

Contacts

Public ContactDr Kasturi Mudoi

Gauhati Medical College and Hospital

faizaahmedtalukdar@gmail.com9864031429

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026