Health Condition 1: L811- Chloasma Health Condition 2: L814- Other melanin hyperpigmentation
Conditions
Interventions
Intervention1: Topical treatment of melasma: It will be right-left facial study. Patient shall apply hydroquinone 2 % on both cheeks daily at night for 8 weeks, 5 days a week for next 4 weeks and 3 d
Sponsors
All India Institute of Medical Science
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with facial melasma with bilateral involvement. 2. Age >= 18 yrs
Exclusion criteria
Exclusion criteria: 1. Pregnancy and Lactation 2. Bleeding tendencies 3. On treatment with any topical or oral treatment of melsma at the time of study or in last two weeks(can be considered after wash-off of 2 weeks) 4. On treatment with laser/light ( can be considered after 4 weeks since last sitting) 5. Obvious infection of skin site 6. Hormone contraception or hormone replacement therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the additional benefit of Platelet Rich Plasma over and above standard hydroquinone cream on melasma reduction. To assess whether the recurrence free period is prolonged after application of platelet rich plasma therapy. To assess the side-effects occurring after the intervention.Timepoint: 4 weeks, 8 weeks, 12 weeks, 16 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| To look at quality of life of patients suffering from melasma and how treatment influences quality of lifeTimepoint: 16 weeks | — |
Countries
India
Contacts
Public ContactDr Neelam Chhajed
All India Institute Of Medical Sciences
Outcome results
None listed