Skip to content

Changes in placenta and uterine artery blood flow in growth restricted fetus.

Association of preterm placental calcification with Uterine Artery Doppler changes in fetal growth restriction.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/07/026288
Enrollment
110
Registered
2020-07-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O098- Supervision of other high risk pregnancies

Interventions

None listed

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Cases- 1) Singleton pregnancy with no gross congenital anomaly in level II scan. 2) Patients at 28 to 35 weeks period of gestation with excellent dates as corroborated by a)Clinical information of known last menstrual period b) 28 to 30 days cycle c) Availability of first trimester ultrasound 3) Estimated fetal weight Controls- Estimated fetal weight between 50th and 90th percentile according to the Intergrowth 21 Standards

Exclusion criteria

Exclusion criteria: Severe maternal disease such as a) Severe anemia b) Rh Isoimmunization (positive Indirect Coombs Test in Rh negative pregnancy) c) Ante partum hemorrhage (APH) due to either placenta previa or abruption d) Heart disease in pregnancy e) Gestational Diabetes Mellitus or Type 1/2 Diabetes Mellitus f) Prelabor Rupture of The Membranes (PROM)

Design outcomes

Primary

MeasureTime frame
1)Grade III placental calcification according to Grannumâ??s classification 2)Uterine Artery Doppler PI more than 50th percentileTimepoint: USG at the time of enrolment and within 2weeks of delivery

Secondary

MeasureTime frame
Adverse perinatal outcome which will be defined by any one of 1.Low birth weight (LBW) 2.Apgar score less than 7 at 5 minutes after birth 3.Cesarian Section for Intrapartum Fetal Compromise (CS-IFC) 4.Meconium Stained Liquor (MSL) 5.Admission to NICU for Hypoxic Ischemic Encephalopathy 6.Intrauterine Fetal Death (IUD) 7.Neonatal Cord Blood pHTimepoint: USG at the time of enrolment and within 2weeks of delivery

Countries

India

Contacts

Public ContactDr Sakshi Aggarwal

Maulana Azad Medical College

tyagishakun@gmail.com9968604484

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026