Health Condition 1: O754- Other complications of obstetric surgery and procedures
Conditions
Interventions
Intervention1: Injection Noradrenaline Bitartrate: Injection Noradrenaline Bitartrate,intravenous,as 5 micrograms per ml.1ml of the drug given as boluses to treat each systolic blood pressure reading
Sponsors
Dr Prerona Saha
Dr Chandita Konwar
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients willing to participate in the study 2.American Society of Anaesthesiologists physical status 2 3.Women with uncomplicated singleton pregnancy scheduled for elective caeserean section under spinal anaesthesia 4.Women aged 18years and more
Exclusion criteria
Exclusion criteria: 1.Women not developing post-spinal hypotension(defined as 20% or more decline in sysytolic arterial pressure from baseline value or absolute value of less than 100 mm Hg) 2.Women with medical conditions(diabetes,hypertensive diseases or pre-eclampsia,cardiovascular diseases,cerebrovascular diseases,renal impairment) 3.Patients having placenta praevia 4.Parturients with fetal malformations 5.On prolonged drug therapy like monoamine oxidase inhibitors,tricyclic anti-depressants 6.Systolic arterial pressure less than 100mm Hg 7.Estimated fetal weight less than 2.5kg or more than 4.5kg 8.Women with height and weight less than 10% or more than 95% for respective age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of bolus doses of phenylephrine and noradrenaline on umbilical cord blood pHTimepoint: At delivery of the baby before the first cry | — |
Secondary
| Measure | Time frame |
|---|---|
| APGAR score of the babyTimepoint: at 1minute and 5minutes;Changes in maternal heart rate,systolic arterial pressure and mean arterial pressureTimepoint: After subarachnoid block every 3minutes till the delivery of baby;Incidence of maternal complications-Nausea,vomiting,chest discomfortTimepoint: from administration of drug till the end of surgery | — |
Countries
India
Contacts
Public ContactDr Chandita Konwar
Gauhati Medical College and Hospital
Outcome results
None listed