Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere Health Condition 2: B342- Coronavirus infection, unspecified
Conditions
Interventions
Intervention1: Group L: Tablet Lithium carbonate 600mg twice daily as add on therapy with Tablet Hydyoxychloroquine 400mg once daily with or without Azithromycin 500mg once daily for 5 days
Control In
Sponsors
Maulana azad medical college
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 70yrs 2.Positive Covid test report as per reverse transcriptase polymerase chain reaction (RT PCR) of oronasopharyngeal swabs. 3.Respiratory rate more than 30 per minute. 4.SpO2 93% or less.
Exclusion criteria
Exclusion criteria: 1.Known case of hypothyroidism 2.Renal insufficiency; Serum creatinine levels more than 1.3 mg/dl 3.Cardiac arrhythmia and cardiac disease 4.Patients on NSAID 5.Known history of QTc prolongation on ECG 6.Contraindication or allergy to hydroxychloroquine 7.Retinal eye disease 8.Pregnancy/breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MortalityTimepoint: At week 3 | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Time taken for conversion to Covid negative status 2.Morbidity 3. Adverse events iii.Adverse drug monitoringTimepoint: 1.From day of report of first sample i.e.day 0, day 3, day 6 2.During stay in hospital i.e. day 3, day 6 3. During stay in hospital, day 3,day 6, day 10 | — |
Countries
India
Contacts
Public ContactDr Sumit Sural
Maulana Azad Medical College and associated Lok Nayak Hospital
Outcome results
None listed