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To study hypotensive properties of dexmedetomidine versus clonidine for induced hypotension in patients undergoing functional endoscopic sinus surgeries.

Comparison of hypotensive properties of dexmedetomidine versus clonidine for induced hypotension during functional endoscopic sinus surgery : A randomized double blind interventional study at SMS Medical College, Jaipur during 2019-2021

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/026186
Enrollment
70
Registered
2020-06-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J00-J99- Diseases of the respiratory system

Interventions

Intervention1: Dexmedetomidine: Loading dose- 1mcg/kg intravenous Infusion dose-1mcg/kg/hr intravenous Duration of surgery 60-70 minutes Control Intervention1: Clonidine: Loading dose-2 mcg/kg intrave

Sponsors

Department of anaesthesiology SMS Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA grade 1 and 2 2.Body weight 45 to 65 kg 3.Undergoing elective resection of nasal polyps ( duration 60 to 70 minutes)

Exclusion criteria

Exclusion criteria: 1.History of allergy to drugs 2.Preexisting bleeding or coagulation disorders 3.History of hypertension, CAD, hepatic or renal disorder 4.Lack of consent 5.CSF Leak

Design outcomes

Primary

MeasureTime frame
To assess and compare the haemodynamic parameters like heart rate, systolic blood pressure,diastolic blood pressure and mean arterial blood pressurefrom base line at different time intervals in both the groups.Timepoint: To assess and compare the haemodynamic parameters like heart rate, systolic blood pressure,diastolic blood pressure and mean arterial blood pressurefrom base line at different time intervals in both the groups.—

Secondary

MeasureTime frame
1. To assess and compare the quality of intra operative surgical field in both the groups. 2.To assess and compare emergence time, sedation score,VAS scoreand time to first rescue analgesia demand in post operative period. 3.To find out and compare the proportion of cases with complications.Timepoint: Assessment of intraoperative bleeding at 10mins,20mins,30mins,40mins, 50mins,60mins,70mins ;1. To assess and compare the quality of intra operative surgical field in both the groups. 2.To assess and compare emergence time, sedation score,VAS scoreand time to first rescue analgesia demand in post operative period. 3.To find out and compare the proportion of cases with complications.Timepoint: Assessment of intraoperative bleeding at 10mins,20mins,30mins,40mins, 50mins,60mins,70mins—

Countries

India

Contacts

Public ContactDr Priya Sharma

SMS Medical College and attached group of hospitals

prshrm585@gmail.com7023505643

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026