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Comparison of pain relief after lower abdominal surgeries using dexmedetomidine and nalbuphine with bupivacaine in spinal anaesthesia

A study to compare the efficacy of intrathecal dexmedetomidine versus nalbuphine as an adjuvant to 0.5% hyperbaric bupivacaine for post operative analgesia in lower abdominal surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/06/026160
Enrollment
80
Registered
2020-06-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N72- Inflammatory disease of cervix uteri Health Condition 2: K36- Other appendicitis

Interventions

Intervention1: Intrathecal block: Duration of analgesia is assessed and duration of study is around 1 year Control Intervention1: Dexmedetomidine 10 mcg and Nalbuphine 1 mg with Bupivacaine Heavy 0.5%

Sponsors

J L N Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients belonging to ASA grade 1 and 2 Informed consent undergoing infraumbilical surgery

Exclusion criteria

Exclusion criteria: Patientâ??s refusal Uncooperative patients Patient undergoing caesarean section Any known hypersensitivity or contraindication to Bupivacaine, Dexmedetomidine and Nalbuphine hydrochloride Local pathology at the site of injection or disability limiting the performance of spinal block History of convulsion, bleeding disorder, severe neurological deficit, thyroid disorder Patient with history of respiratory, cardiac, hepatic or renal disease (necessitating classification in ASA Class III or above) Patients having a history of significant neurological, psychiatric, or neuromuscular disorders

Design outcomes

Primary

MeasureTime frame
Duration of analgesiaTimepoint: 1 year

Secondary

MeasureTime frame
Onset and two segment regression of sensory block. Onset and duration of motor block. Peri-operative sedation score Haemodyanamic changes. Adverse effect if any. Timepoint: 1 year

Countries

India

Contacts

Public ContactDrArvind Khare

JLN Medical college, Ajmer

arvindkhare68@gmail.com9414306114

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026