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Implantation of donor corneal lenticule in patients with advanced keratoconus using femtosecond laser and collagen cross linking.

Femtosecond Laser Assisted Corneal Intrastromal Lenticule Implantation with Collagen Crosslinking in Advanced Keratoconus - A pilot prospective interventional study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/026137
Enrollment
10
Registered
2020-06-25
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H186- Keratoconus

Interventions

Intervention1: Femtosecond Intrastromal Lenticule Implantation: Insertion of a corneal lenticule obtained from patients undergoing Small Incision Lenticule Extraction(SMILE) into Patients cornea in a

Sponsors

Dr R P Center for Ophthalmic Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients above 18 Years of age 2.Patients with Keratoconus with corneal thickness between 350 -400 microns 3.Patients intolerant to Contact Lens use 4.Cone size 5.Patients willing to give consent for the procedure

Exclusion criteria

Exclusion criteria: 1.Patients unwilling to give consent 2.Patients with corneal scarring/healed hydrops. 3.Patients with active allergic disease. 4.Patients with co existing posterior segment pathology. 5.Patients with collagen vascular disease or immunocompromised status. 6.One eyed patients.

Design outcomes

Primary

MeasureTime frame
Uncorrected visual AcuityTimepoint: 1week, 3 months, 6 months—

Secondary

MeasureTime frame
Best Corrected Visual AcuityTimepoint: 1week, 3 months, 6 months;Change in Corneal biomechanical RigidityTimepoint: 1week, 3 months, 6 months;Change in Corneal Thickness and TopographyTimepoint: 1week, 3 months, 6 months;Fit and Tolerance to Contact LensTimepoint: 1week, 3 months, 6 months—

Countries

India

Contacts

Public ContactDr Prasoon Pradeep

Dr R P Center of Ophthalmic Sciences

sinharaj1@gmail.com01126546466

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026