Health Condition 1: A418- Other specified sepsis
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1 Age > 18 years 2 Received first dose of antibiotics in last 24 hours . 3 Patients not received any antibiotics.
Exclusion criteria
Exclusion criteria: 1. Patientâ??s / guardians not giving consent 2. If planned for prolonged antibiotic therapy ( >3 weeks) 3. Expected ICU Length of stay 4. Suspected viral, parasites and tuberculosis infection 5. Severely immune-compromised patients like HIV (CD4 count cells/mm) 6. Neutropenic patients ( 7. Solid organ transplant, Bone marrow transplant 8. Patients on steroid therapy or started on steroid therapy during the study 9. Patients with concomitant haematological diseases (haematological malignancies, autoimmune thrombocytopenic purpura, reactive thrombocytosis, and hypersplenism etc.) 10. Patients received platelets or whole blood transfusion in previous 24 h 11. Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DELTA PCT AND MPV VALUESTimepoint: BEFORE STARTING ANTIBIOTICS(BASELINE) AND AFTER STARTING ANTIBIOTICS (UP TO 7 DAYS) | — |
Secondary
| Measure | Time frame |
|---|---|
| 7 DAYS MORTALITYTimepoint: BEFORE STARTING ANTIBIOTICS(BASELINE) AND AFTER STARTING ANTIBIOTICS (UP TO 7 DAYS) | — |
Countries
India
Contacts
AIIMS RAIPUR