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To compare change in lab value of mean platelet volume with the lab value of procalcitonin for guiding antibiotic therapy in patient with sepsis and septic shock.

Correlation of Delta Mean Platelet Volume with Delta Procalcitonin in guiding antibiotic management in sepsis and septic shock patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/06/026105
Enrollment
30
Registered
2020-06-24
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A418- Other specified sepsis

Interventions

None listed

Sponsors

AIIMS RAIPUR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Age > 18 years 2 Received first dose of antibiotics in last 24 hours . 3 Patients not received any antibiotics.

Exclusion criteria

Exclusion criteria: 1. Patientâ??s / guardians not giving consent 2. If planned for prolonged antibiotic therapy ( >3 weeks) 3. Expected ICU Length of stay 4. Suspected viral, parasites and tuberculosis infection 5. Severely immune-compromised patients like HIV (CD4 count cells/mm) 6. Neutropenic patients ( 7. Solid organ transplant, Bone marrow transplant 8. Patients on steroid therapy or started on steroid therapy during the study 9. Patients with concomitant haematological diseases (haematological malignancies, autoimmune thrombocytopenic purpura, reactive thrombocytosis, and hypersplenism etc.) 10. Patients received platelets or whole blood transfusion in previous 24 h 11. Pregnant or breastfeeding women.

Design outcomes

Primary

MeasureTime frame
DELTA PCT AND MPV VALUESTimepoint: BEFORE STARTING ANTIBIOTICS(BASELINE) AND AFTER STARTING ANTIBIOTICS (UP TO 7 DAYS)

Secondary

MeasureTime frame
7 DAYS MORTALITYTimepoint: BEFORE STARTING ANTIBIOTICS(BASELINE) AND AFTER STARTING ANTIBIOTICS (UP TO 7 DAYS)

Countries

India

Contacts

Public ContactDrChinmaya Kumar Panda

AIIMS RAIPUR

chinmaya.panda06@gmail.com8098007711

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026