Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: NIL: NIL
Sponsors
Akshaya
Eligibility
Inclusion criteria
Inclusion criteria: Individuals willing to take part in the study Subjects who are clinically and histopathologically diagnosed with Oral leukoplakia. Subjects who are clinically diagnosed with OSMF. Healthy individuals free from systemic illness. Healthy individuals free from systemic illness and willing to take part in the study are included in control group.
Exclusion criteria
Exclusion criteria: 1. Patients with oral cancer 2. Previously treated potentially malignant disorders like oral leukoplakia, OSMF and lichen planus. 3. Having history of significant psychosis/ cognitive impairment 4. Patients with salivary gland disorders causing xerostomia. 5. Patient with acute illness or terminally ill patients. 6. Pregnant women and lactating mother. 7. Patients with systemic diseases which include diabetes, rheumatoid arthritis and hypertension which alter MMP 9 levels. 8. Patients on long term steroid therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| There is increase in the salivary level of MMP-9 in OSMF, Oral leukoplakia and controlsTimepoint: AFTER RUNNING SAMPLE IN ELISA | — |
Secondary
| Measure | Time frame |
|---|---|
| salivary levels of MMP-9 as diagnostic biomarkers for patients with Oral leukoplakia and OSMFTimepoint: AFTE RUNNING SAMPLE IN ELISA | — |
Countries
India
Contacts
Public ContactJAGAT REDDY
INDIRA GANDHI INSTITUTE OF DENTAL AL SCIENCES
Outcome results
None listed