A study to compare two different methods of pain relief techniques ( giving a pain killer called Lidocaine through the vein and giving pain killer around the layers of spinal cord at the back for abdominal surgeries performed by keyhole method)

Continuous Intravenous Lidocaine infusion or Thoracic Epidural Analgesia for postoperative pain in Laparoscopic Anterior Resection: A Comparison

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/06/026096

Enrollment

Registered

2020-06-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- All patients above 18 years of age undergoing Laparoscopic Anterior Resection/Low Anterior Resection/ Ultra Low Anterior Resection for cancerous/non cancerous colonic lesions. Health Condition 2: C19- Malignant neoplasm of rectosigmoidjunction

Interventions

Intervention1: 2% IV Lidocaine: Intraoperative continuous intravenous Lidocaine infusion at 2mg/kg bolus followed by 2mg/kg infusion till 30 minutes postoperative. Control Intervention1: Thoracic Epid

Eligibility

Inclusion criteria

Inclusion criteria: 1.All patients undergoing laparoscopic Anterior Resection/ Low Anterior Resections/ Ultra Low Anterior Resection for either cancerous / non cancerous lesions. 2.Age > 18 yrs 3.ASA 1 & 2

Exclusion criteria

Exclusion criteria: â?? ASA 3 & 4 â?? Electrolyte disturbances â?? Allergy to local anaesthetic â?? Seizure disorder â?? Anti-arrhythmic drug intake within 1 week before surgery â?? Psychiatric disorders â?? Steroid treatment â?? Chronic opioid treatments â?? Conversion to laparotomy

Design outcomes

Primary

Measure	Time frame
Postoperative pain score at various intervals using Visual Analogue Score(VAS) Timepoint: VAS at 2,4,8,12,24 hours postoperative	—

Secondary

Measure	Time frame
1)Quality of recovery using Qor 15 score 2)Use of intravenous rescue analgesia ( total opiods used) 3)Length of hospital stay 4)Side effects - â?? with IV Lidocaine- hypotension, bradycardia, syncope, seizures. â?? with TEA - hypotension, epidural catheter misplacement, nerve root injury, urinary retention Timepoint: QoR score measured preoperative and 24-48 hours postoperative	—

Countries

India

Contacts

Public ContactNamitha B J

Christian Medical College

tonythomson@cmcvellore.ac.in9500242412

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026