Health Condition 1: null- Patient with American Society of Anaesthesiologists Physical status 1 and 2 posted for elective surgery under general anaesthesia
Conditions
Interventions
Intervention1: normal saline: placebo
Intervention2: preanaesthetic single infusion of dexmedetomidine: dexmedetomidine - alpha 2 agonist, used as sedation
Intervention3: Intravenous infusion: single
Sponsors
M S RAMAIAH MEDICAL COLLEGE
Eligibility
Inclusion criteria
Inclusion criteria: - Age between 20 and 60 years. - American Society of Anaesthesiologists Grade 1 and 2. - Patients undergoing surgeries under general anaesthesia.
Exclusion criteria
Exclusion criteria: - Patients allergic to study drug. - Patients undergoing laparoscopic surgeries. - Body Mass Index > 35 kg/m2. - Patients on beta blockers,sedatives or stimulant drugs. -Patients with history of psychiatric illness,alcohol abusers,altered mentation or epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effect of preanaesthetic administration of dexmedetomidine on isoflurane consumption.Timepoint: At the end of the surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess effect of dexmedetomidine on intraoperative haemodynamic stability and recovery profile.Timepoint: Baseline,every 5 minutes after infusion of study drug/placebo till end of anaesthesia heart rate,blood pressure,oxygen saturation,bispectral index values were noted. Postoperative recovery profiles were assessed using modified aldrete score at immediate postop,30 and 60 minutes. | — |
Countries
India
Contacts
Public ContactRESHMA B M
M.S.RAMAIAH MEDICAL COLLEGE
Outcome results
None listed