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Study to compare different drugs with different routes in routine surgeries to compare blood circulation responses during tracheal intubation

TO COMPARE THE EFFICACY OF INTRAVENOUS CLONIDINE , LIGNOCAINE NEBULIZATION AND A COMBINATION OF BOTH FOR ATTENUATION OF PRESSOR RESPONSE TO LARYNGOSCOPY AND TRACHEAL INTUBATION

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/026078
Enrollment
75
Registered
2020-06-23
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J958- Other intraoperative and postprocedural complications and disorders of respiratory system, not elsewhere classified

Interventions

Intervention1: intravenous clonidine versus lignocaine nebulization for attenuation of pressor response to laryngoscopy and tracheal intubation in patients undergoing elective surgeries: to evaluate t

Sponsors

Sri Guru Ram Das Institute Of Medical Sciences And Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 or 2 Mallampatti grade 1 or 2

Exclusion criteria

Exclusion criteria: Patient refusal Anticipated and unanticipated difficult airway Hypertension, ischemic heart disease,pregnancy and patients receiving antihypertensives, sympathomimetics,antidepressants and vagomimetics Known allergy to study drugs

Design outcomes

Primary

MeasureTime frame
To Evaluate The Efficacy Of Intravenous Clonidine And Lignocaine Nebulization For Attenuation Of Pressor Response To Laryngoscopy And Tracheal Intubation In Terms Of Heart Rate,Blood Pressure,Oxygen Saturation And ECG ChangesTimepoint: Baseline,Pre-induction,Every 1 Min For First 10 Minutes And Then Every 10 Minutes Till The End Of Surgery—

Secondary

MeasureTime frame
To Study The Incidence Of Intra-operative Complications Associated With Study DrugsTimepoint: Intraoperatively—

Countries

India

Contacts

Public ContactDr Manbir Kaur

Sri Guru Ram Das Institute Of Medical Sciences And Research

drchawla30@yahoo.co.in9915530033

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026