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Comparison of drug esmolol and clonidine for suppression in heart rate and blood pressure after endotracheal tube placement.

A comparative study of intravenous clonidine versus esmolol for attenuation of hemodynamic response associated with laryngoscopy and intubation in abdominal surgeries under general anaesthesia: A randomised double blind interventional study at sms hospital jaipur during year 2109-20

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/026033
Enrollment
72
Registered
2020-06-22
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K00-K95- Diseases of the digestive system

Interventions

Intervention1: Attenuation of hemodynamic response after laryngoscopy and intubation by drug esmolol or clonidine: Comparative study of intravenous clonidine versus esmolol for attenuation of hemodyna

Sponsors

Department of Anaesthesiology sms medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 & A2 Elective abdominal surgeries

Exclusion criteria

Exclusion criteria: 1-Unwilling to participate in study 2-patient with difficult airway 3-patient known allergic to test drug 4-history of medication affecting heart rate and blood pressure 5-heart rate less than 60 6-bleeding disorder

Design outcomes

Primary

MeasureTime frame
1-Mean heart rate 2-Mean systolic blood pressure 3-Mean diastolic blood pressure 4-Mean arterial blood pressure Timepoint: Hemodynamic variables at 1- base line 2-before study drug 3-after study drug 4-before incubation 5- 1minute 3 minute 5 minute and 10 minute post Intubation

Secondary

MeasureTime frame
Side effectsTimepoint: post operative side effects At 1hour 6hour 12 hour and 24 hour

Countries

India

Contacts

Public ContactDr satyaprakash

Sms medical college

Suncha87@yahoo.co.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026