Evaluation of effectivness of membrane made from human platelet concentrate with bioresorable ones using demineralised bone graft in treatment of periodontal defects

Comparative Evaluation Of Platelet Rich Fibrin Matrix membrane(PRFM) and Collagen membrane with Demineralized Freeze Dried Bone Allograft in Class II Furcation Defects

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/06/025979

Enrollment

Registered

2020-06-18

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: PRFM with DFDBA bone allograft: Platelet Rich Fibrin Matrix Membrane with Demineralized Freeze Dried Bone Allograft will be placed in 12 subjects having Class II Furcation Defects Contr

Eligibility

Inclusion criteria

Inclusion criteria: 1)Presence of Class II furcation defect involving either buccal or lingual surfaces of the mandibular molars as determined by clinical and radiographic evaluation. 2)Presence of 3)Presence of 4)The experimental tooth should have proximal bone height coronal to the inter-radicular bone level. 5)Presence of sufficient amount of keratinized tissue. 6)The experimental tooth should have intact tooth surfaces adjacent to the furcation area and should have a normal response to the electric pulp test. 7)The gingival margin of the experimental tooth should be coronal to the furcation fornix. 8)Patients with no complicated medical history 9)Radiographic evidence of furcation defects in the molars (buccal ,lingual ,mesiobuccal or distobuccal).

Exclusion criteria

Exclusion criteria: 1)Patients who are non-compliant to periodontal maintenance program 2)Patients who are smokers or use any other tobacco products. 3)Patients exhibiting tooth mobility for the selected tooth. 4)Confirmed allergy to the graft material, local anesthetics, chlorhexidine, antibiotics and analgesics . 5)Previous history of any periodontal regenerative therapy at the selected site. 6)Pregnant or lactating females. 7)Patients having infectious diseases such as hepatitis, HIV or tuberculosis. 8)Patients with previous systemic conditions and pregnant females.

Design outcomes

Primary

Measure	Time frame
Radiographic Bone Fill in Furcation Defects at 6 months Post surgeryTimepoint: Radiographic Bone Fill in Furcation Defects at 6 months Post surgery	—

Secondary

Measure	Time frame
Gain in Clinical Attachment Level (CAL) Reduction in Probing Pocket Depth(PPD)Timepoint: 6 months	—

Countries

India

Contacts

Public ContactDrPrasad v Dhadse

Datta Meghe Institute of Medical Sciences

drprasaddhadse@gmail.com9822689401

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026