Study to compare opioid based anaesthesia versus combination of ketmaine and magnesium on pain relief and recovery in laparoscopic surgeries

A prospective randomised study to compare opioid based general anaesthesia (OA) versus opioid free general anaesthesia (OFA)using magnesium sulphate and ketamine in laparoscopic surgeries. - OFAOA

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/06/025929

Enrollment

108

Registered

2020-06-17

Start date

Unknown

Completion date

Unknown

Last updated

2023-12-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Injection magnessium sulphate (MgSO4): Injection magnessium sulphate (MgSO4) 40mg/kg intravenous 10 minutes prior to induction in the OFA group over 10 minutes (administered only once a

Eligibility

Inclusion criteria

Inclusion criteria: - BMI - ASA physical status 1 or 2 - Posted for elective Laparoscopic surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: Patient refusal - Patient with ASA physical status 3 or 4 - Pregnant female and lactating mothers - Patient with known allergy to study drugs - Emergency surgeries

Design outcomes

Primary

Measure	Time frame
1.OFA versus OA for intraoperative analgesic requirements. 2.To study whether the suggested combination limits the adverse effects of both groups. 3.OFA versus OA analgesia requirement over 24 hours using VAS scale. Timepoint: 0 hours, 3,6, 12 24 hours	—

Secondary

Measure	Time frame
4. OFA versus OA for intraoperative pressor response at laryngoscopy and extubation.Timepoint: 0 hours immediate post operative, 3,6 ,12 and 24 hours after surgery	—

Countries

India

Contacts

Public ContactMuktabai

Ruby hall clinic, pune

drnita610@yahoo.com9823721982

Outcome results