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Local application of Povidone Iodine solution in nose and oral gargle for house hold contacts of COVID19 cases

Povidone Iodine Gargle and Intranasal application: A Quasi-Experimental study to reduce the spread of coronavirus infection in community with Covid-19 positive clusters.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/025928
Enrollment
204
Registered
2020-06-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Povidone Iodine: 2% Povidone Iodine gargle diluted to 1% (w/v) is used as oropharyngeal gargle. 15 ml of diluted 1% (w/v) Povidone Iodine 4 times daily gargle at prescribed time and i

Sponsors

Dr Sumita Shankar
Lead Sponsor
Dr Rakesh Kakkar
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1- Household (HH) contacts of laboratory confirmed COVID-19 case(s) (more than or equal to one case per HH) 2- Willing to carry out the procedures four times daily for 7 days if provided with the gargle solution. 3- Resident in the area for the last six months. 4- Persons willing to be part of this protocol and sign informed consent.

Exclusion criteria

Exclusion criteria: 1- Allergy (hypersensitivity) to povidone iodine. 2- Currently have or have ever had a thyroid problem, including swelling. 3- Pregnant women and lactating mothers. 4- Persons who are unable to carry out the intervention due to intellectual disability. 5- Persons who are too ill to participate.

Design outcomes

Primary

MeasureTime frame
The Decrease in the attack rate of Primary and Secondary contacts of COVID19 patients and reduction of the Viral Load (Using cycle threshold values of RT PCR at different timelines)Timepoint: 7th day

Secondary

MeasureTime frame
Early recovery from infection and no relapse of infection.Timepoint: 7th and 21 st day

Countries

India

Contacts

Public ContactDr Vivekanand Kattimani

Rangaraya Medical College

sum713@yahoo.com9848184495

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026