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Role of a natural hormone supplement in improving pregnancy rate.

Dehydroepiandrosterone ( DHEA) role in enhancement and maintenance of implantation (DREAM) - Randomized Double Blind Placebo Controlled Trial - DREAM TRIAL

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/025918
Enrollment
140
Registered
2020-06-16
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N972- Female infertility of uterine origin

Interventions

Intervention1: DHEA (Dehydroepiandrosterone): DHEA - 25 mg twice a day for 15 days if serum testosterone is less than 0.2 ng/ml . Control Intervention1: Oral Placebo: PLACEBO appearing similar to the

Sponsors

CRAFT Hospital and Research Centre
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: INCLUSION CRITERIA 1.Women with age more than or equal to 35 years Or 2.women with AMH value less than 1.1 ng/ml or AFC less than 5 to 7 Whose serum testosterone less than 0.2 ng/ml

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA Women with PCOS. Women with serum Testosterone �0.2 ng/ml women with BMI more than 30kg/mt2 Women with Congenital and untreated or acquired uterine abnormality. Women with Untreated hydrosalpinx. Women with Thrombophilia. Women with uncontrolled endocrine and heamatological dysfunction. PGTA embryos Those planning embryo transfer as per endometrial receptivity ERA Thin endometrium less than 8mm in index cycle. severe male factor infertility. Difficult embryo transfer. Cases where only poor quality embryos are available. Couple with genetic and chromosomal abnormality

Design outcomes

Primary

MeasureTime frame
Ongoing pregnancy rate or Live birth rateTimepoint: After 20 weeks

Secondary

MeasureTime frame
b-HCG positive rate ,clinical pregnancy rate , miscarriage rate.Timepoint: 6 weeks, 20 weeks

Countries

India

Contacts

Public ContactDr Noushin Abdul Majiyd

Craft Hospital And Research Centre

drnoshinashraf@gmail.com9544240002

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 14, 2026