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Monitoring the effects of Antihypertensives(ACE Inhibitors / ARBS)in patients undergoing surgey

Perioperative management of preoperative therapy with ACE inhibitors/ARBS - An obsevational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/06/025892
Enrollment
100
Registered
2020-06-16
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I10-I16- Hypertensive diseases

Interventions

None listed

Sponsors

Kasturba Medical College Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult hypertensive patients, of either gender on treatment with angiotensin converting enzyme inhibitors or Angiotensin receptor blockers who are scheduled for elective surgery will be enrolled in the study.

Exclusion criteria

Exclusion criteria: PREGNANT WOMEN AGE TERMINALLY ILL

Design outcomes

Primary

MeasureTime frame
incidence of deviation of mean blood pressure 30% from the baseline (as recorded during preoperative visit) intraoperatively Timepoint: Baseline (preop) Immediate preop After induction After intubation 1 min 2 min 3 min 5 min 10 min 15 min 30 min 1 hr 2 hr Hourly till extubation Before extubation

Secondary

MeasureTime frame
1)Incidence of deviation of mean blood pressure 30% from the baseline (as recorded during preoperative visit) postoperatively 2)Need for treatment of deviation in blood pressure (with vasoconstrictors/vasodilators) intraoperatively and postoperatively 3)Any other adverse event attributable to ACE inhibitor/ARB continuation/discontinuation. Timepoint: After extubation 1 min 5 min 30 min 1 hr 6 hr 12 hr 18 hr 24 hr

Countries

India

Contacts

Public ContactDr Reshma P Tharsis

Kasturba Medical College,Manipal

anitharshenoy@gmail.com9880842121

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026