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Effect of lignocaine infusion and pain relief

Effect of intravenous lignocaine on perioperative opioid consumption for pain and intraoperative hemodynamics in laparoscopic surgery - LIHOC

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/025839
Enrollment
90
Registered
2020-06-12
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K811- Chronic cholecystitis Health Condition 2: K36- Other appendicitis

Interventions

Intervention1: Lignocaine: Intravenous lignocaine 1.5mg/kg bolus followed by an infusion of 1.5mg/kg/hour during the intraoperative period Intervention2: Dexmedetomidine: 1ug/kg bolus followed by 0.5u

Sponsors

Vinayaka Missions Research Foundation
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American society of Anesthesiologists physical status 1 and 2, BMI 22-30kg/m2,

Exclusion criteria

Exclusion criteria: ASA physical status 3 and 4 Emergency surgery, significant cardiac, respiratory and neurological illness, patients on chronic antiarrythmic drugs, psychotropic drugs, allergy to local anesthetics

Design outcomes

Primary

MeasureTime frame
post operative VAS scoreTimepoint: 0 min, 15 min, 30 min, 1 hour, 2 hour, 6 hour,12 hour, 24 hour—

Secondary

MeasureTime frame
Analgesia consumption (inj diclofenac, inj tramadol)Timepoint: Hourly till 6 hours, 4th hourly till 24 hours;intraoperative heartrate and blood pressureTimepoint: every 5 minutes throughout surgery—

Countries

India

Contacts

Public ContactArun Dev

Vinayaka Missions Research Foundation

dr.arundev646@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026