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A comparative study of safety and efficacy of a local anaesthesia combined with two different adjuvants ; given as USG guided nerve block, in patients undergoing upper limb orthopaedic surgery. ?

“A comparative study of safety and efficacy of 0.5% Ropivacaine combined with either Dexmedetomidine or Clonidine as adjuvant ; given as USG guided supraclavicular brachial plexus block, in patients undergoing elective upper limb orthopaedic surgery. ?

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/025823
Enrollment
50
Registered
2020-06-11
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S529- Unspecified fracture of forearm

Interventions

Intervention1: Ropivacaine with clonidine: Patients who will receive 29ml ropivacaine 0.5% and 1ml clonidine(50mcg) Control Intervention1: Ropivacaine with dexmedetomidine: Patient who will receive 29

Sponsors

Dr Sampurnanand Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I & II of body weight 30 to 80 kg, undergoing upperlimb orthopaedic surgery of less than two hours duration. Free from any associated chronic systemic illness.

Exclusion criteria

Exclusion criteria: Uncooperative patient Pregnant or lactating mother Neurological deficit in operative limb with chronic pain or on long term analgesics Patient having hypersensitivity or contraindication to Ropivacaine/ Dexmedetomidine/ Clonidine Local pathology at the site of injection All disability limiting the performance of block

Design outcomes

Primary

MeasureTime frame
1. To compare the duration of analgesia,onset of sensory and motor block of 0.5% Ropivacaine combined with either Dexmedetomidine or Clonidine as adjuvants injected perineurally. 2. Number of Rescue analgesic given in 24 hours in both groups 3. Total dose of rescue medication consumption (tramadol and Diclofenac) in 24 hrs.Timepoint: Assessment of block quality by calculation of composite score of bromage scale and duration of analgesia was recorded by patient response.

Secondary

MeasureTime frame
1. NRS pain scores at rest (NRS-R) & at movement (passive/active) NRS-M of operated upper limb in first 24 hours. 2. Patient’s satisfaction score. 3. Any complications / adverse effects/side effects of block. 4. Any changes inNIBP,PR&SpO 2 in first 24 hours.Timepoint: Assessment of block quality by calculation of composite score of bromage scale and duration of analgesia was recorded by patient response.

Countries

India

Contacts

Public ContactDr Anjali Singh

Dr S. N. Medical college, jodhpur

fatehbhati@yahoo.co.in9414127176

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026