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A prophylactic interventional study to determine the possible protective effect of Siddha Polyherbal formulation Kabasura Kudineer against the COVID 19 on intermittent, month-long consumption by public with close contacts to COVID patients and frontline workers in Tamil Nadu, India

A prospective Non randomized open label controlled intervention study on the effect of Polyherbal Siddha formulation Kabasura kudineer as a prophylactic measure among high risk population (Health care workers/ Containment zone population) exposed to COVID 19

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/025769
Enrollment
40000
Registered
2020-06-09
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Kabasura kudineer: 5- 10gms of Kabasura kudineer drug boiled with 240ml of water will be reduced to 60 ml, filtered and Consumed within 3 hours. Concoction will be freshly prepared for

Sponsors

National institute of Siddha Ministry of AYUSH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All the willing frontline health workers, police personnel and other public servants inclusive of those with direct / primary contacts with COVID positives (High risk and moderate risk exposures).

Exclusion criteria

Exclusion criteria: Not willing to sign informed consent. Subjects taking Steroid treatment and or any kind of immunosuppressive therapy Subjects participating in any other clinical study or having participated in any other study 1 month prior to screening in the present study.

Design outcomes

Primary

MeasureTime frame
Percentage of participants protected during the outbreak of COVID 19 compared between the Kabasura Kudineer taken and Standard of Care taken groupsTimepoint: Assessment will be done at Baseline and 30th day from the start of Prophylactic intervention.

Secondary

MeasureTime frame
General and specific health status as assessed. â?? Immune Status and Function as assessed by ISQ â?? Progression of disease in the participants who turned COVID 19 positiveTimepoint: 6 months

Countries

India

Contacts

Public ContactDr N J Muthukumar

National institute of Siddha

drsureshherbal@gmail.com9962571137

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026