Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: Drug sofosbuvir: sofosbuvir 400 mg twice daily for 10 days in all eligible study subjects along with standard of care including tablet hydroxy chloroquine 400 mg twice a day on day 1 fo
Sponsors
Dr N Babu
Eligibility
Inclusion criteria
Inclusion criteria: Patients more than 18 years of age and proven COVID-19 by RT-PCR for SARS CoV-2 with one of the following criteria 1. requiring hospitalization with acute organ dysfunction(or) 2. SaO2 in room air 3. Infiltrates in Chest X rays or CT Chest or Ultrasound evidence of Pneumonia and
Exclusion criteria
Exclusion criteria: 1. Patients with mild symptoms (only fever and cough) and no risk factors 2. Or not requiring any hospitalization, 3. patient with comorbid illnesses with less than 50% survival rate at 1 year (Chronic End Stage Organ Disease). 4. Patient on dialysis or Chronic kidney disease stage 5 5. Patient on drugs: amiodarone, phenytoin, phenobarbital and rifampicin 6.Patient with HBsAg (or) anti Hbc Antibody Positive 7.Patient with anti HCV antibody positive 8.Patient not willing to give consent. 9. Pregnancy/ lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mortality of the study subjectsTimepoint: during hospitalisation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.number of hospitalisation days 2.number of intensive care unit days 3.need for invasive ventilation. 4.number of ventilator days. 5.period of viral clearanceTimepoint: during hospitalisation | — |
Countries
India
Contacts
Public ContactBabu N
Vijaya Medical and Educational Trust
Outcome results
None listed