Study on the effect of Yashtimadhu ghee for minimizing the radiation toxicity in patients of oropharyngeal cancer.

A randomized controlled trial to evaluate the efficacy of Yashtimadhu ghrita application for minimizing the radiation induced toxicity in patients with oropharyngeal squamous cell carcinoma.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/06/025757

Enrollment

Registered

2020-06-09

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C10- Malignant neoplasm of oropharynx Health Condition 2: C10- Malignant neoplasm of oropharynx

Interventions

Intervention1: Yashtimadhu ghrita: Patients in the intervention arm will be advised to smear yashtimadhu ghrita in their oral and oropharyngeal areas 4 times daily for a period of 4 weeks after the r

Eligibility

Inclusion criteria

Inclusion criteria: Patients who had undergone radical radiation therapy/ chemo radiation for carcinoma oropharynx

Exclusion criteria

Exclusion criteria: 1.Patients diagnosed with diabetes mellitus 2.Presenting with trismus 3.Patients who are not willing to give informed consent.

Design outcomes

Primary

Measure	Time frame
To assess the effectiveness of the Ghrita In controlling oral mucositis In controlling pain In minimising antibiotic and anti fungal requirements In reducing analgesic usage In reducing radiation induced dryness In improving oral hygiene Timepoint: Day 1,15 days, 28 days and follow up after 6 month.	—

Secondary

Measure	Time frame
NILTimepoint: NOT APPLICABLE	—

Countries

India

Contacts

Public ContactDr Swathy V

Regional Cancer Centre, Medical College Campus, Thiruvananthapuram, 695011, Kerala

ramdasrcc@gmail.com9447042309

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026