Health Condition 1: R198- Other specified symptoms and signsinvolving the digestive system and abdomen
Conditions
Interventions
Intervention1: To evaluate if combination of low dose rocuronium with magnesium sulphate and ketamine provides better intubating conditions at 60 seconds compared to high dose rocuronium alone.: One
Sponsors
Amrita Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Age 18 - 65 years ASA PS 1-2 BMI 18.5 - 24.9 kg/m2 Mallampati grade 1-2 Elective surgery under general anaesthesia requiring intubation
Exclusion criteria
Exclusion criteria: Neuromuscualr disease Renal insufficiency Hepatic insufficiency Allergy to study drugs Breast feeding or pregnancy Anticipated difficult airway Heart block Recent histort of URTI
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate if combination of low dose rocuronium 0.6 mg/kg IV with magnesium sulphate 30 mg/kg IV and ketamine 1 mg/kg IV provides better intubating conditions compared to high dose rocuronium 0.9 mg/kg IV alone,at 60 seconds.Timepoint: At 60 seconds after induction. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare hemodynamic response mean arterial pressure and heart rate between the two groupsTimepoint: At baseline, after induction, after intubation, 3 minutes and 6 minutes thereafter. | — |
Countries
India
Contacts
Public ContactDimple Elina Thomas
Amrita Institute of medical sciences
Outcome results
None listed