A clinical trial to study the effects of two skin antiseptics, Chlorhexidine and Povidone-Iodine(Betadine) in women undergoing emergency cesarean delivery.

Comparing the efficacy of Chlorhexidine Gluconate Versus Povidone-Iodine as Skin Antiseptic for prevention of Surgical Site Infection in women undergoing emergency Caesarean Delivery: A Randomized Control Trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/06/025722

Enrollment

876

Registered

2020-06-09

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O860- Infection of obstetric surgical wound

Interventions

Intervention1: Chlorhexidine gluconate IP equivalent to 0.5% w/v of chlorhexidine gluconate and Isopropyl Alcohol 70% v/v purified water IP q.s.: Skin preparation will be done by centrifugal scrubbin

Eligibility

Inclusion criteria

Inclusion criteria: Antenatal women at >=34 weeks gestational age undergoing emergency Cesarean delivery

Exclusion criteria

Exclusion criteria: 1)Patients denying consent 2)Known allergy to one or both of the agents. 3)Patients with skin lesions adjacent to the operative site. 4)Women with chorioamnionitis, pyelonephritis, urinary tract infection, and mastitis.

Design outcomes

Primary

Measure	Time frame
To estimate the incidence of surgical site infection with use of Chlorhexidinegluconate compared with povidone iodine as skin antiseptic in women undergoing emergency caesarean delivery.Timepoint: followed postoperatively after 48 hours,1 week and 30 days.	—

Secondary

Measure	Time frame
To compare the incidence of the below outcomes 1)Duration of hospital stay. 2)Requirement for re-suturing. 3)Re-admission resulting from infection. 4)Pyrexia. Timepoint: followed postoperatively after 48 hours, 1 week and 30 days.	—

Countries

India

Contacts

Public ContactGabbeta Spandana

All India Institute of Medical Sciences, Bhubaneswar

drpruthwiraj@gmail.com9438884132

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026