Health Condition 1: E840- Cystic fibrosis with pulmonary manifestations
Conditions
Interventions
Intervention1: Nebulized vancomycin: Intervention will be given for a duration of 1 month Patient will receive nebulized vancomycin. Injectable form of vancomycin will be used.250 mg of vancomycin wil
Sponsors
Jagat Jeevan Ghimire
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: Children of cystic fibrosis with early Staphylococcus aureus infection.Early infection defined as a positive culture in current culture or culture within 6 months that was not treated on prior visits which may be either the first-lifetime positive culture or new emergence of the organism after at least 1 year of documented negative cultures
Exclusion criteria
Exclusion criteria: 1. Children with Current Co-colonisation with pseudomonas spp. 2. Children receiving anti-staphylococcal treatment in 4 weeks prior to screening and enrolment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication of Staphylococcus aureus from the respiratory sampleTimepoint: 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effect of antimicrobials therapyTimepoint: 3 months;Clinical ,nutritional ,radiologic severityTimepoint: 3 months;Number of hospital admissions and emergency visitsTimepoint: 3 months;Pattern of lung function testTimepoint: 3 months;Quality of life scoreTimepoint: 3 months | — |
Countries
India
Contacts
Public ContactSushil Kumar Kabra
All India institute of medical sciences
Outcome results
None listed