A STUDY DONE TO COMPARE THE EFFECT OF CLONIDINE OR DEXMEDETOMIDINE AS AN ADDITIVE TO LOCAL ANAESTHETIC DRUG LEVOBUPIVACAINE FOR CAUDAL ANALGESIA IN CHILDRENS UNDERGOING SURGERIES BELOW UMBLICUS.

A COMPARATIVE STUDY OF CLONIDINE AND DEXMEDETOMIDINE AS AN ADJUVANT TO LEVOBUPIVACAINE FOR CAUDAL ANALGESIA IN CHILDREN UNDERGOING BELOW UMBILICAL SURGERIES: A RANDOMISED DOUBLE BLIND CONTROLLED TRIAL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/06/025684

Enrollment

100

Registered

2020-06-08

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: CAUDAL ANALGESIA: TO COMPARE CLONIDINE AND DEXMEDETOMIDINE AS AN ADJUVANT TO LEVOBUPIVACAINE FOR CAUDAL ANALGESIA IN CHILDREN UNDERGOING BELOW UMBILICAL SURGERIES Control Intervention1:

Eligibility

Inclusion criteria

Inclusion criteria: Age 3 to 8years. ASA physical status 1 or 2. Posted for elective below umbilical surgeries under general anaesthesia.

Exclusion criteria

Exclusion criteria: History of developmental delay/ mental retardation Anomalies of spine and central nervous system Contraindications to regional anaesthesia. History of allergy to drugs used in study. History of bleeding disorders Infection at injection site Patients found unfit for surgery in pre anaesthetic evaluation

Design outcomes

Primary

Measure	Time frame
Time to requirement of first rescue analgesic in the postoperative periodTimepoint: Pain status using Wong-Baker pain scale evaluated at 0minutes, 30minutes, 1, 1.5, 2, 4, 8, 24 hours postoperatively	—

Secondary

Measure	Time frame
1.Incidence of complications like hypotension (fall in SBP20% from baseline), bradycardia (HR 60/min), prolonged motor block, nausea and vomiting, apnoea, desaturation (SpO290%) and urinary retention. 2.Duration of motor block and its characteristics 3.Postoperative sedation scores Timepoint: Postoperatively motor block using Modified Bromage score and degree of sedation by Ramsay sedation score evaluated at 0minutes, 30minutes, 1, 1.5, 2, 4, 8, 24 hours	—

Measure

Time frame

1.Incidence of complications like hypotension (fall in SBP20% from baseline), bradycardia (HR 60/min), prolonged motor block, nausea and vomiting, apnoea, desaturation (SpO290%) and urinary retention. 2.Duration of motor block and its characteristics 3.Postoperative sedation scores Timepoint: Postoperatively motor block using Modified Bromage score and degree of sedation by Ramsay sedation score evaluated at 0minutes, 30minutes, 1, 1.5, 2, 4, 8, 24 hours

—

Countries

India

Contacts

Public ContactSIDDARTH AGRAWAL

CHACHA NEHRU BAL CHIKITSALYA

shilpa.mamc@gmail.com9811168878

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026