study to compare effectiveness of drugs in preventing hemodynamic alterations during functional endoscopic sinus surgery procedure under general anaesthesia

A COMPARATIVE STUDY BETWEEN MAGNESIUM SULPHATE,LIGNOCAINE AND PROPOFOL FOR ATTENUATION OF HEMODYNAMIC RESPONSE DURING FUNCTIONAL ENDOSCOPIC SINUS SURGERY UNDER GENERAL ANAESTHESIA

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/06/025648

Enrollment

105

Registered

2020-06-05

Start date

Unknown

Completion date

Unknown

Last updated

2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J329- Chronic sinusitis, unspecified Health Condition 2: H470- Disorders of optic nerve, not elsewhere classified Health Condition 3: J339- Nasal polyp, unspecified Health Condition 4: J349- Unspecified disorder of nose and nasal sinuses

Interventions

Intervention1: PROPOPOL ,MAGNESIUM SULPHATE,LIGNOCAINE: A COMPARATIVE STUDY BETWEEN MAGNESIUM SULPHATE,LIGNOCAINE AND PROPOFOL FOR ATTENUATION OF HEMODYNAMIC RESPONSE DURING FUNCTIONAL ENDOSCOPIC SINU

Eligibility

Inclusion criteria

Inclusion criteria: Both sex. ASA 1 and 2 patients aged between 18 TO 55 Valid written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. ASA grade III and IV. 3. Known allergy to study drug. 4. Systemic hypertension. 5. Diabetes mellitus. 6. Patients with coagulopathies or receiving drugs influencing blood coagulation. 7. Patients with coronary artery disease,renal hepatic or cerebral insufficiency. 8. Patients on adrenergic blocking drugs. 9. Current psychiatric disorder or any respiratory disorders. 10. Pregnant patients.

Design outcomes

Primary

Measure	Time frame
To assess the hemodynamic attenuation response during the surgeryTimepoint: To assess the hemodynamic attenuation response during the surgery	—

Secondary

Measure	Time frame
To assess the intraoperative blood field To assess the requirement of neuromuscular blocking agent. To assess the recovery time after the procedureTimepoint: 3 years	—

Countries

India

Contacts

Public ContactDr gooty sunanda

ESIC MEDICAL COLLEGE HOSPITAL AND SUPERSPECIALTY

sunanda_gooty@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026