Comparison of efficacy of erector spinae plane block with paravertebral block for postoperative pain management in patients undergoing breast cancer surgeries

Comparison of efficacy of erector spinae plane block with paravertebral block for postoperative analgesia in patients undergoing breast cancer surgeries

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/06/025611

Enrollment

Registered

2020-06-04

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C509- Malignant neoplasm of breast of unspecified site

Interventions

Intervention1: USG guided erector spinae plane block in patients undergoing breast cancer surgeries: ESP block will be placed with patient in lateral position with side to be operated towards up. Und

Eligibility

Inclusion criteria

Inclusion criteria: This study will be conducted in adult female patients of age 18 - 60 years weighing > 50 kgs, fulfilling criteria of American Society of Anaesthesiology (ASA) physical status i and ii undergoing elective modified radical mastectomy (MRM) for breast cancer under general anaesthesia with controlled ventilation.

Exclusion criteria

Exclusion criteria: 1. coagulation disorder, local infection, allergy to study drugs 2. anatomic deformity of spine or chest wall 3. pregnant patient 4.morbid obesity 5. liver or renalinsufficiency, respiratory/ cardiac/ psychiatric disease.

Design outcomes

Primary

Measure	Time frame
Duration of Analgesia- time from administration of the block till time of administration of first rescue analgesia to the patient will be noted (primary objective).Timepoint: Preoperative vitals to be noted at time 0. Intraoperative vitals to be noted at before block, 10, 20, 30, 40, 50, 60, 90, 120, 150, 180 mins after the block. postoperative: 1. VAS assessment at 0,1,2,4,6.,12,24 hours 2. PONV score assessed at 0,6,12,24 hours.	—

Measure

Time frame

Duration of Analgesia- time from administration of the block till time of administration of first rescue analgesia to the patient will be noted (primary objective).Timepoint: Preoperative vitals to be noted at time 0. Intraoperative vitals to be noted at before block, 10, 20, 30, 40, 50, 60, 90, 120, 150, 180 mins after the block. postoperative: 1. VAS assessment at 0,1,2,4,6.,12,24 hours 2. PONV score assessed at 0,6,12,24 hours.

—

Secondary

Measure	Time frame
1) Visual Analogue Scale (VAS) 2) Total intraoperative requirement of fentanyl 3) Total amount of tramadol required in first 24 hours postoperatively 4) Postoperative nausea and vomiting 5) Adverse effects if any 6) Patient satisfaction using numeric rating scale (nrs) 7) Number of dermatomal segments blocked postoperatively Timepoint: VAS at 0,1,2,4,6,12,24 hours Postoperative nausea and vomiting at 0,6,12,24 hours	—

Measure

Time frame

1) Visual Analogue Scale (VAS) 2) Total intraoperative requirement of fentanyl 3) Total amount of tramadol required in first 24 hours postoperatively 4) Postoperative nausea and vomiting 5) Adverse effects if any 6) Patient satisfaction using numeric rating scale (nrs) 7) Number of dermatomal segments blocked postoperatively Timepoint: VAS at 0,1,2,4,6,12,24 hours Postoperative nausea and vomiting at 0,6,12,24 hours

—

Countries

India

Contacts

Public ContactArjun Singh

Safdarjung hospital and Vardhman Mahavir Medical College

nidhi.agrawal1970@gmail.com9811030408

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026