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TO compare the effect of technique of pain relief on recurrence of cancer after breast surgery

Effect of Regional Anaesthesia on immune response, recurrence and metastasis in breast cancer surgery: a prospective randomized control study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/025582
Enrollment
500
Registered
2020-06-03
Start date
Unknown
Completion date
Unknown
Last updated
2022-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50-C50- Malignant neoplasms of breast

Interventions

Intervention1: Group RA (regional analgesia group): Patients will receive US guided regional block along with general anesthesia (GA) using 10 cm (100 mm) needle Control Intervention1: Group GA (gener

Sponsors

ICMR
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA physical status III or less 2. Primary breast cancer for unimastectomy/breast conservation surgery 4. With or without lymph node dissection 5. Women younger than 75 years

Exclusion criteria

Exclusion criteria: age more than 75 years ASA status IV or more Patient refusal Coagulopathy Patients with history of allergy to study drugs.

Design outcomes

Secondary

MeasureTime frame
1. Biochemical recurrence 2. Persistent postoperative painTimepoint: 1. blood test will be done baseline, after completion of surgery and after 24 hours. 2. pain will be assessed e (0 min),30 min, 1 hour, 24 hours, 1 month, 6 month and 12 month.

Primary

MeasureTime frame
Non-occurrence of breast cancer at the end of 3-yearsTimepoint: Patients will be examined every six months till three years to screen for local and systemic breast cancer recurrence by clinical assessment at the end of 3-years.

Countries

India

Contacts

Public ContactNishkarsh Gupta

AIIMS

drnishkarsh@rediffmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026