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Comparison of effects of adding either of Two drugs, namely Buprenorphine or Phenylephrine in addition to usually given Local drug Bupivacaine for Anaesthesia for Surgeries of Upper limb with the help of Ultrasound Guidance

COMPARISON OF EFFECT OF BUPRENORPHINE VERSUS PHENYLEPHRINE AS AN ADJUVANT TO BUPIVACAINE IN ULTRASOUND GUIDED SUPRACLAVICULAR BLOCK

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/06/025552
Enrollment
90
Registered
2020-06-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M966- Fracture of bone following insertion of orthopedic implant, joint prosthesis, or bone plate

Interventions

Intervention1: 0.5% BUPIVACAINE WITH BUPRENORPHINE 3 µg/kg: STUDY OF SINGLE INJECTION OF 20 ml OF 0.5% BUPIVACAINE WITH BUPRENORPHINE 3 µg/kg FOR BLOCKADE OF BRACHIAL PLEXUS NERVES IN THE SUPRACLAVI

Sponsors

Sri Venkateshwaraa medical college hospital and research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)ASA1 and 2 2)age 20 to 70 yrs 3)both sex 4)patients undergoing elective upperlimb surgeries below shoulder.

Exclusion criteria

Exclusion criteria: 1)patient refusal 2)infection at the site of injection 3)coagulations disorders 4)hypersensitivity to local anaesthetics and opioids 5)patients with history of hypertension, myocardial infarction and periperal neuropathy

Design outcomes

Primary

MeasureTime frame
DURATION OF ANALGESIATimepoint: The time from the onset of complete sensory block of Scale 0 to the first perception of pain by the patient within 24 hours after the commencement of block

Secondary

MeasureTime frame
1. Onset of sensory blockade 2.Onset of motor blockade 3. Duration of sensory blockade 4. Duration of Motor blockade 5. Quality of analgesia 6. VAS pain score Timepoint: 1.Assessed till 30 minutes after the block 2.Assessed till 30 minutes after the block 3.Assessed within 24 hours from block 4.Assessed within 24 hours from block 5.Assessed within 30 minutes after block 6.Commencing 60 min after the block, VAS will be assessed at hourly intervals for the next 4hrs and 3 hourly intervals till 24 hrs

Countries

India

Contacts

Public ContactDR B JALAKANDAN

SRI VENKATESHWARAA MEDICAL COLLEGE,HOSPITAL AND RESEARCH CENTER

jalakandan1681@gmail.com9994976064

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026