Health Condition 1: I051- Rheumatic mitral insufficiency
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: RHD patients with symptomatic long standing persistent atrial fibrillation in the age group of >= 18years with LA diameter of more than 4.5 cm in heart failure with NYHA functional class >= II, despite optimal medical therapy will be included in the study.
Exclusion criteria
Exclusion criteria: 1-Severe valvular lesions requiring surgery or intervention 2- Significant Coronary artery disease 3-Ongoing infection 4-Pregnancy 5-Severe co-morbidies limiting life expectancy 6-Untreated hypothyroidism, hyperthyroidism 7-Mental or physical inability to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To study improvement in exercise capacity as measured by 6-minute walk test distance (6MWT) following HBP/LBBAP with AVJ ablation Timepoint: 3 MONTHS | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)To Study change in functional class before and after HBP/LBBAP with AVJ ablation.2)To study improvement in cardiac biomarker NT-proBNP3months after HBP/LBBAP and AVJ ablation.3)To study number of heart failure related hospital admissions following HBP/LBBAP and AVJ ablation.4)To study improvement in left ventricular ejection fraction(modified Simpsonâ??s method)/pulmonary artery systolic pressure (PASP)/tricuspid regurgitation/Mitral regurgitation after HBP/LBP and AVJ ablation.Timepoint: 3 MONTHS | — |
Countries
India
Contacts
AIG Hospital