Health Condition 1: K701- Alcoholic hepatitis
Conditions
Interventions
Intervention1: Saturated Fat (Desi Ghee): Most of the western studies have used saturated fat in the form of lard, beef, cocoa butter which is not possible in the Indian scenario therefore we choose t
Sponsors
Department of Biotechnology
Eligibility
Inclusion criteria
Inclusion criteria: -All patients with Severe Alcoholic Hepatitis -Aged between 18-60 years -Maddrey Score of >32 -Last Intake of alcohol from 1 day to 30days -Patients who agree for complete alcohol abstinence from the day of enrollment
Exclusion criteria
Exclusion criteria: Patients with -Maddrey Score of 54 -Comorbidities- Diabetes, Hypertension, Coronary Artery Disease, Chronic Kidney Disease, Hypothyroid -Continuing Alcohol intake- Non-compliant patients -Patients predominantly on Desi Ghee -With Constipation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| -Improved Cirrhosis Dysbiosis Ratio Timepoint: 2 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Decreased endotoxin levels Timepoint: 2 months;Improved Lipid profile Timepoint: 2 months;Improvement in Clinical outcome -Decreased bilirubin levels -Decreased AST and ALT levels -Improved Maddrey ScoreTimepoint: 2 months;Improvement of Nutritional StatusTimepoint: 2 months;Increased adiponectin levels Timepoint: 2 months;Reduced inflammation Timepoint: 2 months | — |
Countries
India
Contacts
Public ContactDr Jaya Benjamin
Institute of Liver and Biliary Sciences
Outcome results
None listed