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To compare between muscle strength and ultrasound characteristics of muscle in South Indian Individuals with and without early chronic kidney disease.

Association between muscle strength and ultrasound measured muscle thickness and echo intensity in South Indian Individuals with and without early chronic kidney disease.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/05/025407
Enrollment
372
Registered
2020-05-28
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N182- Chronic kidney disease, stage 2 (mild)

Interventions

Control Intervention1: NIL: NIL

Sponsors

Adithya Shetty
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria: For Cases: • Subjects detected with early stage chronic kidney disease defined by KDIGO guidelines. Stage G2 and G3a; eGFR ranging from 45 to 89 ml/min/1.73 m2. For Controls: • Healthy volunteers above the age of 20 years referred for routine general ultrasound. • Controls will be screened by taking history and going through medical records to meet inclusion criteria.

Exclusion criteria

Exclusion criteria: 1.Athletes, body builders and physically active individuals. 2.History of upper limb surgery. 3.Hereditary neuromuscular disorders. 4.History of malignancy. 5.History of diabetes. 6.History of thyroid disorders 7.History of renal/hepatic/cardiovascular disease. 8.History of steroid intake. 9.Any other rheumatological diagnosis. 10.Osteoarticular injuries.

Design outcomes

Primary

MeasureTime frame
Mean and standard deviations will be calculated. Differences in dependent variables between men and women will determined using unpaired student t tests. Correlation between muscle thickness, echo intensity, strength and physical characteristics will be done using Pearsonâ??s correlation coefficients. Multiple linear regression analysis will be applied to assess independent associations. Statistical significance will be assessed by evaluating the p value. Timepoint: June 2021—

Secondary

MeasureTime frame
Normal pattern of muscle thickness, echo intensity and strength changes with respect to different age groups and BMI will be derived. Association of muscle thickness and echo intensity with muscle strength in various age groups will be derived. Changes in muscle thickness, echo intensity and muscle strength in early CKD patients as compared to the normal individuals will be known. Timepoint: August 2021—

Countries

India

Contacts

Public ContactDr Vinay R

Kasturba Medical College Manipal

lakshmikanth.hk@manipal.edu9740730283

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026