Health Condition 1: S822- Fracture of shaft of tibia
Conditions
Interventions
Intervention1: Use of Platelet Rich Fibrin(PRF) in Open fractures of tibia: After wound debridement and external fixator application,PRF will be injected into fracture site and for dressing of wound i
Sponsors
Maulana Azad Medical College
Eligibility
Inclusion criteria
Inclusion criteria: 1.Upper, middle and lower third fractures of tibia 2.Open fractures of Gustilo Anderson Grade 2 and 3A with a wound size of 1-10 cm². 3.Gustilo Anderson grade 3B where wound can be closed
Exclusion criteria
Exclusion criteria: 1.Infected wounds 2.Grossly contaminated wounds from farmyard or sewage contamination. 3.Exposed Bone at the fracture site 4.Bone Loss 5.Comminuted and segmental fracture 6.Intra-articular extension of fracture. 7.Pathological fractures. 8.External fixators which span proximal to the knee joint. 9.HIV, Diabetes, Pregnancy / Lactation/ Patient on Steroids. 10.Hemoglobin less than 10g% 11.Coagulopathy 12.Platelet count less than 2,00,000/mm3 13.Patient of unsound mind or undergoing psychiatric treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of wound status in open fractures of tibia with the use of platelet rich fibrin.Timepoint: Wound assessment will be recorded on day 3, day 7 and then every week till wound healing. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assessment of union of open fractures of tibia with platelet rich fibrin.Timepoint: X-rays will be done to assess the fracture union once a month for 6 months. | — |
Countries
India
Contacts
Public ContactSubhashis Mandal
Maulana Azad Medical College, New Delhi
Outcome results
None listed