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Comparison between two drugs pregabalin and gabapentin for pain relief following operation.

Comparison between gabapentin and pregabalin as premedication before spinal anesthesia in lower abdominal surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/05/025386
Enrollment
78
Registered
2020-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R448- Other symptoms and signs involvinggeneral sensations and perceptions

Interventions

Intervention1: gabapentin: preemptive analgesia with one oral dose of 600mg gabapentin Control Intervention1: pregabalin: preemptive analgesia with one oral dose 150mg pregabalin

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients belonging to either sex of age 18 to 65 years of ASA status I and II scheduled to undergo elective lower abdominal surgery under spinal anaesthesia

Exclusion criteria

Exclusion criteria: Pregnant and breast feeding women Preexisting cardiac disease renal disorder hepatic disease psychiatric and coagulation disorder Patient refusal to participate Any contraindication to spinal anaesthesia History of allergy to study drugs Those receiving long term analgesic therapy Any other contraindications for using pregabalin and gabapentin

Design outcomes

Primary

MeasureTime frame
Prolonging postoperative analgesiaTimepoint: 24 hours postoperative period—

Secondary

MeasureTime frame
Adverse outcomesTimepoint: 24 hours postoperative period;Haemodynamic changesTimepoint: 24 hours postoperative period;Need for rescue analgesicTimepoint: 24 hours postoperative period—

Countries

India

Contacts

Public ContactDr Chiranjib Bhattacharyya

IPGMER

bhattach1@yahoo.com9433508030

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026