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Genetic susceptibility of a preterm infant to develop retinopathy of prematurity

Genetic Polymorphism and risk of development of retinopathy of prematurity

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/05/025378
Enrollment
105
Registered
2020-05-27
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H351- Retinopathy of prematurity

Interventions

Control Intervention1: Single Nucleotide Polymorphism in TNF and VEGF gene: Single Nucleotide Polymorphism in TNF and VEGF gene in preterm infants and their correlation with development of ROP

Sponsors

Government Medical College Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Infants with 1. Gestation age of 34 weeks or less 2. Birth weight of 1750 grams or less 3. Gestation age of 34-36 weeks or 1750-2000 g birthweight with risk factors for ROP

Exclusion criteria

Exclusion criteria: Infants with 1. Media opacities 2. Major Congenital abnormalities

Design outcomes

Primary

MeasureTime frame
The association of VEGF and TNF gene polymorphism with risk of development of retinopathy of prematurity Timepoint: 6 months—

Secondary

MeasureTime frame
The association of VEGF and TNF gene polymorphism with severity of retinopathy of prematurityTimepoint: Day 14 Month 3 Month 6—

Countries

India

Contacts

Public ContactDr Mannat Giran

Government Medical College & Hospital Chandigarh

subina_navya@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026