Comparison of 1% clotrimazole vs coconut oil in superficial dermatophytoses

Comparison of topical application of 1% clotrimazole vs coconut oil as an adjuvant to systemic antifungals in superficial dermatophytoses- a hospital based open label study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/05/025375

Enrollment

100

Registered

2020-05-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B359- Dermatophytosis, unspecified

Interventions

Intervention1: 1% Clotrimazole Cream: half of the study group based on randomized numbers will be given topical 1% Clotrimazole Cream twice daily local application for total of 12 weeks along with sys

Eligibility

Inclusion criteria

Inclusion criteria: clinically diagnosed cases of dermatophytosis with koh mount and culture positive who have given written informed consent

Exclusion criteria

Exclusion criteria: Patients refusing to participate in study. Patients suffering from any chronic debilitating systemic diseases Patients with other chronic cutaneous disorders. patients with any contraindication to the systemic therapy being given. Patients with dermatophyte infection of nails and hair (Tinea capitis and Onychomycosis Patients with more than 10 % body surface area involvement.

Design outcomes

Primary

Measure	Time frame
to assess efficacy of coconut oil in superficial dermatophytosis by assessing clinical cure and mycological cureTimepoint: basekin week 0 versus week 12	—

Secondary

Measure	Time frame
To compare KOH mount (septate fungal hyphae vs no sepatae fungal hyphae). To compare growth on culture media.To compare VAS score for itch.To compare DLQI questionnaire scoresTimepoint: To compare KOH mount (septate fungal hyphae vs no sepatae fungal hyphae) at week 0,2,4,8,12.To compare growth on culture media at week 0,8. To compare VAS score for itch at 0,2,4,8,12 weeks. To compare DLQI questionnaire scores at 0,4,12 weeks	—

Measure

Time frame

To compare KOH mount (septate fungal hyphae vs no sepatae fungal hyphae). To compare growth on culture media.To compare VAS score for itch.To compare DLQI questionnaire scoresTimepoint: To compare KOH mount (septate fungal hyphae vs no sepatae fungal hyphae) at week 0,2,4,8,12.To compare growth on culture media at week 0,8. To compare VAS score for itch at 0,2,4,8,12 weeks. To compare DLQI questionnaire scores at 0,4,12 weeks

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Countries

India

Contacts

Public ContactAakriti Chawla

shri ram murti smarak institute of medical sciences bareilly

drpratikg@rediffmail.com9503241184

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026