Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere
Conditions
Interventions
Intervention1: Guduchi Ghan Vati: Dose: 500mg- BD(Twice a day),
Route of Administration- Oral,
Duration- 30 days
Control Intervention1: Not applicable: Not applicable
Sponsors
Dr SR Rajasthan Ayurved University Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: 1. All hospitalized cases above 18-60 years of age, clinically diagnosed with corona virus disease 2019 (Covid19) and who are asymptomatic or having Mild symptoms. 2. Participants who can take medicines orally. 3. Patients willing to provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Cases of severe vomiting which would affect oral administration of medicine difficult. 2. Cases of respiratory failure and requiring mechanical ventilation. 3. Patients having Alanine Transaminase (ALT) or Aspartate Transaminase (AST) > 5 times the upper range of normal limits. 4. Patients with COVID-19 in critical condition or ARDS or NIAD 8 â??point ordinal score-2 (Hospitalized, on invasive mechanical Ventilation or extra corporeal membrane oxygenation 5. Combined organ failure requiring ICU monitoring. 6. Patients with uncontrolled Diabetes Mellitus, (HbA1c more than 8.0), Malignant Hypertension (systolic BP more than 180 and diastolic 110), Chronic Renal Failure and those on immunosuppressive medication. 7. Patients with history of malignancy, IHD, CAD, triple vessel disease, history of CABG, Stroke, etc. 8. Any other condition, which as per the investigator would jeopardize the outcome of the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Clinical cure rate: Time to get a negative status of Covid-19. (defined as viral load of respiratory specimen negative for two consecutive times when tested in an interval of two days) [Time frame 1 month]Timepoint: [Time frame 1 month] | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Duration of fever and each of the respiratory symptoms 2.Improvement in hematological and laboratory parameters (lymphocyte count, Hs-CRP, ESR, TC,DC, Absolute lymphocyte count, LFT,RFT,IL-6, Ig E, Ig-G,Ig-M, LDH, Platelet count), 3.No of cases Reporting any ADR/AE 4.Number of patients referred. 5.Number of cases that required invasive or non-invasive oxygen therapy during the intervention. 6.Number of cases that progressed to multi- organ failure while under clinical trial.Timepoint: [Time Frame: 1 month] | — |
Countries
India
Contacts
Public ContactDR SANJAY SRIVASTAVA
Dr. S.R. Rajasthan Ayurved University, Jodhpur
Outcome results
None listed