Can irrigation of urethra with povidone iodine before surgery result in decreased urine infections? - A study

Role of pre-operative urethral irrigation with povidone iodine in reducing catheter associated urinary tract infections in patients undergoing urological surgeries: A randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/05/025365

Enrollment

366

Registered

2020-05-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N398- Other specified disorders of urinary system

Interventions

Intervention1: pre-operative urethral irrigation with povidone iodine in addition to standard surgical part preparation: Patients to receive pre operative urethral irrigation with povidone iodine solu

Eligibility

Inclusion criteria

Inclusion criteria: All patients undergoing urologic surgeries involving urethral manipulation (endourological procedures/urethral catheterization) with no significant ( >100000 cfu) growth on urine culture.

Exclusion criteria

Exclusion criteria: Patients unwilling to give consent for inclusion in the study. Age 75 years. Expected indwelling catheter duration of more than 1 week. Emergency procedures. Pre-existing infection focus at the time of surgery. Uncontrolled diabetes mellitus, immune-suppression or any other non-urological disease pre-disposing to higher risk for infections. Urethral reconstructive surgeries or genital/perineal/rectal approach to surgery

Design outcomes

Primary

Measure	Time frame
Incidence of clinical CAUTI post procedureTimepoint: Day 2 and Day 7	—

Secondary

Measure	Time frame
1. Incidence of clinical CAUTI after per-urethral endoscopic urologic surgeryTimepoint: Day 2 and Day 7;2. Incidence of clinical CAUTI after non-endoscopic urologic surgeryTimepoint: Day 2 and Day 7;3. Incidence of symptomatic significant bacteriuria post procedureTimepoint: Day 2 and Day 7;4. Correlation of organisms on swab culture with systemic infection or CAUTI and organisms causing UTITimepoint: Day 2 and Day 7;5. Time to UTI episodeTimepoint: Day 2 and Day 7;6. Hospital readmission rates within 6 weeks post procedureTimepoint: 6 weeks	—

Measure

Time frame

1. Incidence of clinical CAUTI after per-urethral endoscopic urologic surgeryTimepoint: Day 2 and Day 7;2. Incidence of clinical CAUTI after non-endoscopic urologic surgeryTimepoint: Day 2 and Day 7;3. Incidence of symptomatic significant bacteriuria post procedureTimepoint: Day 2 and Day 7;4. Correlation of organisms on swab culture with systemic infection or CAUTI and organisms causing UTITimepoint: Day 2 and Day 7;5. Time to UTI episodeTimepoint: Day 2 and Day 7;6. Hospital readmission rates within 6 weeks post procedureTimepoint: 6 weeks

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Countries

India

Contacts

Public ContactDr Rishi Nayyar

AIIMS, New Delhi

nayyarrishi@gmail.com9811414607

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026