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PRF in diabetic patients with gum disease

Evaluation of Three-dimensional structure and Cytokine distribution of Essence of Platelet-rich fibrin (ePRF) in Diabetic patients with concomitant Chronic Periodontitis: An Electron Microscopic and Biochemical Analysis- A Pilot Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2020/05/025364
Enrollment
20
Registered
2020-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: nil: nil as this is an observational trial Control Intervention1: nil: nil as this is an observational trial

Sponsors

Department of Science and Technology Chandigarh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Group 1T2DM with healthy periodontium No periodontal treatment in the prior 6 months. T2DM patients who have HbA1c levels between greater than 7 % Periodontally healthy subjects Group 2 T2DM with chronic periodontitis Patients with moderate to advanced chronic periodntitis T2DM patients who have HbA1c levels greater than 7 % No periodontal treatment in the prior 6 months. Group 3 Systemically healthy subjects with chronic periodontitis Nondiabetics Patients with moderate to advanced chronic periodntitis No periodontal treatment in the prior 6 months. Group 4 Systemically and periodontally healthy subjects Periodontally and systemically healthy subjects Nondiabetics No periodontal treatment in the prior 6 months.

Exclusion criteria

Exclusion criteria: Any known systemic diseases other than type 2 diabetes mellitus (for Groups 1 & 2) Patient under medicine treatment for at least 6 months except treatment for diabetes Insufficient platelet count ( Tobacco use " Pregnancy

Design outcomes

Primary

MeasureTime frame
Three-dimensional structure under electron microscopeTimepoint: baseline

Secondary

MeasureTime frame
levels of platelet derived growth factor- BBTimepoint: baseline

Countries

India

Contacts

Public ContactDR SHIPRA GUPTA

Oral Health Sciences Centre, PGIMER, CHANDIGARH

teena1472@yahoo.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026