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A clinical trial to study the effect of nerve ablation for pain on knee muscle strength in patients with osteoarthritis

Effect of radiofrequency ablation of genicular nerves on the isokinetic muscle strength of knee joint in patients with osteoarthritis knee: A randomised double blind clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2020/05/025363
Enrollment
60
Registered
2020-05-26
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: radio frequency ablation to genicular nerves: radio frequency ablation will be delivered to superior medial genicular nerve, inferior medial genicular nerve and superior lateral genicul

Sponsors

Post Graduate Institute of Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients having chronic knee osteoarthritis pain having VNRS > 50, KL grading of 2 or more, not responding to physiotherapy or oral analgesics

Exclusion criteria

Exclusion criteria: patients with acute knee pain, history of trauma to the knees, prior knee surgery, connective tissue disorders, neurological or psychiatric disorders, received intraarticular injection with steroid or hyaluronic acid within 3 months, radicular leg pain, taking anticoagulant medications

Design outcomes

Primary

MeasureTime frame
Effects of Radiofrequency ablation of genicular nerves on isokinetic strength of knee jointTimepoint: Baseline, 2 weeks, 1 month, 3 months

Secondary

MeasureTime frame
Reduction in VNRS of knee pain in response to radio frequency ablationTimepoint: baseline, 2 weeks, 1 month and 3 months;Compliance to the suggested physiotherapy regimen assessed by a Likert scaleTimepoint: 2 weeks, 1 month, 3 months;improvement in functionality assessed by WOMAC scale in response to radio frequency ablationTimepoint: baseline, 2 weeks, 1 month, 3 months;patient perception of effect as assessed by GPE scaleTimepoint: 2 weeks, 1 month, 3 months

Countries

India

Contacts

Public ContactDr Jeetinder Kaur Makkar

Post Graduate Institute of Medical Education and Research

jeet1516@gmail.com7087009510

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 5, 2026