To compare pain relief by dexmedetomidine versus dexamethasone when injected into caesarean surgical wound.

Comparison of analgesic efficacy of dexmedetomidine with dexamethasone as adjuvant to bupivacaine for wound infiltration in patients undergoing caesarean section under spinal anaesthesia

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2020/05/025354

Enrollment

Registered

2020-05-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Wound infiltration with dexmedetomidine as adjuvant to bupivacaine in patients undergoing caesarean section under spinal anaesthesia.: Intraoperatively, before closure of the skin, pati

Eligibility

Inclusion criteria

Inclusion criteria: Patients in the age group of 18 to 45 years, belonging to American Society of Anaesthesiologist (ASA) physical status class II or III undergoing caesarean section under spinal anaesthesia

Exclusion criteria

Exclusion criteria: Patients with cardiac, pulmonary, hepatic or renal disease; allergy to any of the study drugs; history of chronic pain or taking any pain medication; inability to comprehend visual analogue scale(VAS) or history of any psychiatric illness

Design outcomes

Primary

Measure	Time frame
To compare the analgesic efficacy of dexmedetomidine with dexamrthasone as adjuvant to bupivacaine for wound infiltration in patients undergoing caesarean section under spinal anaesthesia using the total analgesic requirement in 24 hrsTimepoint: 24h	—

Secondary

Measure	Time frame
1) Time to first analgesic requirement 2) Visual analogue scale score for pain in postoperative period at 0,1,2,6,12 and 24 h 3) Patient satisfaction regarding postoperative analgesia at 24 hTimepoint: 0,1,2,6,12 and 24 h	—

Countries

India

Contacts

Public ContactDr Parul Mullick

VARDHMAN MAHAVIR MEDICAL COLLEGE AND SAFDARJUNG HOSPITAL

parash93@yahoo.com9810606262

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026