Health Condition 1: C509- Malignant neoplasm of breast of unspecified site
Conditions
Interventions
Intervention1: Brahmi ghrita: Brahmi ghrita intervention will be given and the patients which will be randomized into 3 arms, one arm will receive a formulation named Brahmi Ghrita, 2nd arm will rece
Sponsors
Department of AYUSH Extramural Research Scheme Govt of India
Eligibility
Inclusion criteria
Inclusion criteria: 1. Early stage II and III breast cancer patients 2. Age between 18 to 75 years 3. Scheduled to undergo at least 6 cycles of adjuvant chemotherapy followed by adjuvant radiotherapy at HCG hospital. 4. High school education with ability to read and write English
Exclusion criteria
Exclusion criteria: 1. Those with prior h/o depression, major psychiatric illness and Alzheimerâ??s disease and on medication 2. Those with brain metastases 3. Concurrent medical condition likely to influence survival 4. Uncontrolled diabetes, hypertension and autoimmune disease 5. Neurological disorders such as any significant head injury, epilepsy, Parkinsonâ??s disease, neurodegenerative disorders etc. 6. Regular participation in an active behavioral intervention/Ayurveda Nootropic in the last six months 7. H/o recent infections or fever in the past two weeks 8. Those with anemia (Hemoglobin 9. Those with cardiac pacemakers or other incompatible body implants (For f MRI study) 10. Left handedness or mixed handedness 11. Claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| improvement in Cognitive Function will be assessed through Neuropsychological test battery For a subset of 20 patients task based fMRI will be done Timepoint: Baseline assessment soon after the diagnosis 2nd assessment after completion of chemotherapy 3rd assessment after completion of the Intervention (i.e after 3 months of intervention) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Quality of life 2. FACT COG 3. Quality of Life as measured by self-report EORTC QOL C30 4. Stress as measured by Self-report Perceived Stress Scale 5.Heart rate variabilityTimepoint: Baseline assessment soon after the diagnosis 2nd assessment after completion of chemotherapy 3rd assessment after completion of the Intervention (i.e after 3 months of intervention) | — |
Countries
India
Contacts
Public ContactDr Swathi B H
state private university
Outcome results
None listed